MGMT protein (Macaca mulatta) - STRING interaction network

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[Homology]

Score

MGMT

Methylated-DNA--protein-cysteine methyltransferase. (238 aa)

Predicted Functional Partners:

IDH1

0.785

DHDDS

0.775

TRIP12

0.740

IDH2

0.704

TP53

0.683

OGG1

0.641

MLH1

0.627

PCNA

0.627

MSH6

0.607

CDKN1A

0.595

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDKN1A	MGMT	ENSMMUP00000077663	ENSMMUP00000015013	Cyclin-dependent kinase inhibitor 1.	Methylated-DNA--protein-cysteine methyltransferase.	0.595
CDKN1A	PCNA	ENSMMUP00000077663	ENSMMUP00000062455	Cyclin-dependent kinase inhibitor 1.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.976
CDKN1A	TP53	ENSMMUP00000077663	ENSMMUP00000011334	Cyclin-dependent kinase inhibitor 1.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.999
DHDDS	MGMT	ENSMMUP00000040498	ENSMMUP00000015013	Alkyl transferase; Belongs to the UPP synthase family.	Methylated-DNA--protein-cysteine methyltransferase.	0.775
IDH1	IDH2	ENSMMUP00000021152	ENSMMUP00000033268	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.974
IDH1	MGMT	ENSMMUP00000021152	ENSMMUP00000015013	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Methylated-DNA--protein-cysteine methyltransferase.	0.785
IDH1	TP53	ENSMMUP00000021152	ENSMMUP00000011334	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.615
IDH1	TRIP12	ENSMMUP00000021152	ENSMMUP00000041818	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Thyroid hormone receptor interactor 12.	0.461
IDH2	IDH1	ENSMMUP00000033268	ENSMMUP00000021152	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.974
IDH2	MGMT	ENSMMUP00000033268	ENSMMUP00000015013	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Methylated-DNA--protein-cysteine methyltransferase.	0.704
IDH2	TP53	ENSMMUP00000033268	ENSMMUP00000011334	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...]	0.571
IDH2	TRIP12	ENSMMUP00000033268	ENSMMUP00000041818	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	Thyroid hormone receptor interactor 12.	0.484
MGMT	CDKN1A	ENSMMUP00000015013	ENSMMUP00000077663	Methylated-DNA--protein-cysteine methyltransferase.	Cyclin-dependent kinase inhibitor 1.	0.595
MGMT	DHDDS	ENSMMUP00000015013	ENSMMUP00000040498	Methylated-DNA--protein-cysteine methyltransferase.	Alkyl transferase; Belongs to the UPP synthase family.	0.775
MGMT	IDH1	ENSMMUP00000015013	ENSMMUP00000021152	Methylated-DNA--protein-cysteine methyltransferase.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.785
MGMT	IDH2	ENSMMUP00000015013	ENSMMUP00000033268	Methylated-DNA--protein-cysteine methyltransferase.	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.704
MGMT	MLH1	ENSMMUP00000015013	ENSMMUP00000029670	Methylated-DNA--protein-cysteine methyltransferase.	MutL homolog 1.	0.627
MGMT	MSH6	ENSMMUP00000015013	ENSMMUP00000030085	Methylated-DNA--protein-cysteine methyltransferase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.607
MGMT	OGG1	ENSMMUP00000015013	ENSMMUP00000039729	Methylated-DNA--protein-cysteine methyltransferase.	ENDO3c domain-containing protein.	0.641
MGMT	PCNA	ENSMMUP00000015013	ENSMMUP00000062455	Methylated-DNA--protein-cysteine methyltransferase.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.627