Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ACANAggrecan. (2266 aa)    
Predicted Functional Partners:
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif 5.
    
 0.966
ADAMTS4
A disintegrin and metalloproteinase with thrombospondin motifs 4 preproprotein.
    
 0.960
HAPLN1
Hyaluronan and proteoglycan link protein 1.
   
 0.954
TNC
Tenascin C.
   
 0.917
COL2A1
Collagen type II alpha 1 chain.
   
 0.915
MMP13
Matrix metallopeptidase 13.
   
 0.910
DCN
Decorin; May affect the rate of fibrils formation.
   
 0.876
FMOD
Fibromodulin.
    
 0.876
MMP3
Matrix metallopeptidase 3.
   
 0.863
TNR
Uncharacterized protein.
   
 0.855
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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