Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AMBRA1Autophagy and beclin 1 regulator 1. (1238 aa)    
Predicted Functional Partners:
ULK1
Serine/threonine-protein kinase; Serine/threonine-protein kinase involved in autophagy in response to starvation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. APG1/unc-51/ULK1 subfamily.
   
 0.995
BECN1
Beclin 1.
    
 0.994
DDA1
DET1-and DDB1-associated protein 1.
    
 0.990
ATG14
Autophagy related 14.
     
 0.986
BECN2
Beclin 2.
    
 0.984
PIK3R4
Phosphoinositide 3-kinase regulatory subunit 4.
   
 
 0.981
ULK2
Unc-51 like autophagy activating kinase 2.
   
 0.981
PIK3C3
Phosphatidylinositol 3-kinase catalytic subunit type 3.
   
 0.978
PINK1
Serine/threonine-protein kinase PINK1, mitochondrial.
    
 0.971
HUWE1
E3 ubiquitin-protein ligase HUWE1.
    
 0.968
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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