STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FBXW5F-box and WD repeat domain containing 5. (566 aa)    
Predicted Functional Partners:
SKP1-2
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.969
SEC23B
Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily.
    
 
 0.929
POMP
Proteasome maturation protein.
      
 0.881
DDB1
Damage specific DNA binding protein 1.
    
 0.873
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.847
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.806
CASP10
Caspase 10; Belongs to the peptidase C14A family.
      
 0.761
CUL4A
Cullin 4A; Belongs to the cullin family.
    
 0.750
CUL3
Cullin-3; Belongs to the cullin family.
    
 0.707
FBXW9
F-box and WD repeat domain containing 9.
   
 
 0.698
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.