node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRL1 | IL16 | ENSMMUP00000062828 | ENSMMUP00000015164 | Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | 0.645 |
ADGRL2 | IL16 | ENSMMUP00000003384 | ENSMMUP00000015164 | Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | 0.645 |
ADGRL3 | IL16 | ENSMMUP00000003482 | ENSMMUP00000015164 | Latrophilin-3; Belongs to the G-protein coupled receptor 2 family. | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | 0.645 |
CASP3 | CD4 | ENSMMUP00000070295 | ENSMMUP00000069370 | Caspase 3; Belongs to the peptidase C14A family. | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.678 |
CASP3 | IL16 | ENSMMUP00000070295 | ENSMMUP00000015164 | Caspase 3; Belongs to the peptidase C14A family. | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | 0.488 |
CD4 | CASP3 | ENSMMUP00000069370 | ENSMMUP00000070295 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Caspase 3; Belongs to the peptidase C14A family. | 0.678 |
CD4 | IL16 | ENSMMUP00000069370 | ENSMMUP00000015164 | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | 0.967 |
F7FL02_MACMU | IL16 | ENSMMUP00000033547 | ENSMMUP00000015164 | CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | 0.402 |
IL16 | ADGRL1 | ENSMMUP00000015164 | ENSMMUP00000062828 | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | Adhesion G protein-coupled receptor L1; Belongs to the G-protein coupled receptor 2 family. | 0.645 |
IL16 | ADGRL2 | ENSMMUP00000015164 | ENSMMUP00000003384 | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | Adhesion G protein-coupled receptor L2; Belongs to the G-protein coupled receptor 2 family. | 0.645 |
IL16 | ADGRL3 | ENSMMUP00000015164 | ENSMMUP00000003482 | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | Latrophilin-3; Belongs to the G-protein coupled receptor 2 family. | 0.645 |
IL16 | CASP3 | ENSMMUP00000015164 | ENSMMUP00000070295 | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | Caspase 3; Belongs to the peptidase C14A family. | 0.488 |
IL16 | CD4 | ENSMMUP00000015164 | ENSMMUP00000069370 | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] | 0.967 |
IL16 | F7FL02_MACMU | ENSMMUP00000015164 | ENSMMUP00000033547 | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity). | CASPASE_P20 domain-containing protein; Belongs to the peptidase C14A family. | 0.402 |