STRINGSTRING
IL16 protein (Macaca mulatta) - STRING interaction network
"IL16" - Pro-interleukin-16 in Macaca mulatta
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Cooccurence
Coexpression
Experiments
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[Homology]
Score
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4 (By similarity) (1331 aa)    
Predicted Functional Partners:
IKZF1
IKAROS family zinc finger 1 (Ikaros) (519 aa)
     
 
  0.621
LCP2
Lymphocyte cytosolic protein 2 (533 aa)
     
   
  0.611
PTPRC
Protein tyrosine phosphatase, receptor type C (1279 aa)
     
 
  0.607
C15orf26
Cilia and flagella associated protein 161; Chromosome 15 open reading frame 26 (301 aa)
 
       
  0.606
CXCL8
Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus (By similarity); Belongs to the intercrine alpha (chemokine CxC) family (99 aa)
     
   
  0.563
CCL11
Eotaxin; In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3 (By similarity) (97 aa)
     
   
  0.549
IL15
Interleukin-15; Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha (161 aa)
     
   
  0.544
ZNF148
Zinc finger protein 148 (794 aa)
       
      0.541
IL18
Macaca mulatta interleukin 18 (interferon-gamma-inducing factor) (IL18), mRNA (193 aa)
     
   
  0.536
ENSMMUG00000003131
Interleukin-13 (153 aa)
           
  0.533
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Macaca mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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