STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PNKPPolynucleotide kinase 3'-phosphatase. (532 aa)    
Predicted Functional Partners:
POLB
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
    
 0.962
XRCC1
X-ray repair cross complementing 1.
   
 0.959
TTF2
Transcription termination factor 2.
  
 
 0.915
LIG3
DNA ligase.
   
 0.914
TDP1
Tyrosyl-DNA phosphodiesterase 1.
   
 
 0.902
NEIL1
Nei like DNA glycosylase 1.
     
 0.874
NEIL2
Nei like DNA glycosylase 2.
     
 0.827
LIG4
DNA ligase.
   
 0.793
ENSMMUP00000056331
XRCC1_N domain-containing protein.
   
 0.782
RAB36
RAB36, member RAS oncogene family.
      
 0.772
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.