Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PKP4Plakophilin-4 isoform a. (1192 aa)    
Predicted Functional Partners:
CTNNB1
Catenin beta-1.
   
 0.891
CDH8
Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.820
ERBIN
Erbb2 interacting protein.
    
 0.809
JUP
Uncharacterized protein.
   
 0.796
DSP
Desmoplakin.
    
 0.756
CTNNA1
Uncharacterized protein.
   
 0.713
CTNNA3
Catenin alpha-3.
   
 0.713
CTNNA2
Catenin alpha 2.
   
 0.713
VCL
Vinculin.
   
 0.707
CDH5
Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins.
    
 0.696
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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