Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MYF5Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (255 aa)    
Predicted Functional Partners:
PAX3
Paired box 3.
   
 
 0.896
PAX7
Paired box 7.
   
 
 0.894
MEF2C
Myocyte-specific enhancer factor 2C isoform 1.
    
 0.816
MSTN
Growth/differentiation factor 8; Acts specifically as a negative regulator of skeletal muscle growth; Belongs to the TGF-beta family.
   
  
 0.777
MEF2A
Myocyte-specific enhancer factor 2A isoform 2.
    
 0.773
TCF12
Transcription factor 12 isoform a.
    
 0.753
MEF2D
Myocyte-specific enhancer factor 2D.
    
 0.743
EP300
Histone acetyltransferase p300.
    
 
 0.740
TCF4
Transcription factor 4.
    
 0.714
MEF2B
MADS-box domain-containing protein.
    
 0.708
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (24%) [HD]