Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
MMD2Monocyte to macrophage differentiation associated 2. (265 aa)    
Predicted Functional Partners:
ADK
Adenosine kinase.
      
 0.532
SPO11
SPO11 initiator of meiotic double stranded breaks.
      
 0.531
DYSF
Dysferlin.
   
  
 0.513
ANO5
Anoctamin.
      
 0.509
ST8SIA6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6; Belongs to the glycosyltransferase 29 family.
   
  
 0.475
APPL1
Uncharacterized protein.
    
   0.416
APPL2
Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2.
    
   0.416
PAK4
Non-specific serine/threonine protein kinase.
   
    0.410
PAK6
Non-specific serine/threonine protein kinase.
   
    0.410
PAK5
Non-specific serine/threonine protein kinase.
   
    0.410
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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