PRR18 protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COG6	GOLT1A	ENSMMUP00000005980	ENSMMUP00000076782	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	Golgi transport 1A.	0.544
COG6	GOLT1B	ENSMMUP00000005980	ENSMMUP00000055603	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	Uncharacterized protein.	0.544
COG6	KISS1	ENSMMUP00000005980	ENSMMUP00000004863	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	Metastasis-suppressor KiSS-1; Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.	0.468
COG6	PRR18	ENSMMUP00000005980	ENSMMUP00000015358	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	Proline rich 18.	0.468
COG6	SFT2D1	ENSMMUP00000005980	ENSMMUP00000015400	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.	0.468
COG6	STX16	ENSMMUP00000005980	ENSMMUP00000002439	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	Syntaxin-16 isoform a; Belongs to the syntaxin family.	0.919
COG6	STX5	ENSMMUP00000005980	ENSMMUP00000006982	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.891
COG6	YKT6	ENSMMUP00000005980	ENSMMUP00000003265	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	Synaptobrevin-like protein YKT6; Belongs to the synaptobrevin family.	0.777
FAM43B	PRR18	ENSMMUP00000061690	ENSMMUP00000015358	Family with sequence similarity 43 member B.	Proline rich 18.	0.402
GOLT1A	COG6	ENSMMUP00000076782	ENSMMUP00000005980	Golgi transport 1A.	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	0.544
GOLT1A	PRR18	ENSMMUP00000076782	ENSMMUP00000015358	Golgi transport 1A.	Proline rich 18.	0.465
GOLT1A	SFT2D1	ENSMMUP00000076782	ENSMMUP00000015400	Golgi transport 1A.	Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.	0.506
GOLT1B	COG6	ENSMMUP00000055603	ENSMMUP00000005980	Uncharacterized protein.	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	0.544
GOLT1B	PRR18	ENSMMUP00000055603	ENSMMUP00000015358	Uncharacterized protein.	Proline rich 18.	0.465
GOLT1B	SFT2D1	ENSMMUP00000055603	ENSMMUP00000015400	Uncharacterized protein.	Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.	0.472
KISS1	COG6	ENSMMUP00000004863	ENSMMUP00000005980	Metastasis-suppressor KiSS-1; Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	0.468
KISS1	PRR18	ENSMMUP00000004863	ENSMMUP00000015358	Metastasis-suppressor KiSS-1; Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.	Proline rich 18.	0.465
KISS1	SFT2D1	ENSMMUP00000004863	ENSMMUP00000015400	Metastasis-suppressor KiSS-1; Metastasis suppressor protein. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.	Vesicle transport protein; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.	0.465
PRR18	COG6	ENSMMUP00000015358	ENSMMUP00000005980	Proline rich 18.	Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.	0.468
PRR18	FAM43B	ENSMMUP00000015358	ENSMMUP00000061690	Proline rich 18.	Family with sequence similarity 43 member B.	0.402