Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LMBR1Limb development membrane protein 1; Belongs to the LIMR family. (490 aa)    
Predicted Functional Partners:
PRKAG3
Protein kinase AMP-activated non-catalytic subunit gamma 3.
      
 0.768
DNAJC2
DnaJ homolog subfamily C member 2 isoform 1.
      
 0.767
DNAJB2
J domain-containing protein.
   
 
 0.744
ZP2
Zona pellucida glycoprotein 2.
      
 0.670
WNT8B
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.667
SHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
 
    
 0.654
EPRS1
Glutamyl-prolyl-tRNA synthetase.
    
 
 0.625
SLC35F3
Solute carrier family 35 member F3.
      
 0.581
IHH
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
 
    
 0.578
FAM210B
Family with sequence similarity 210 member B.
      
 0.554
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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