Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HHEXHematopoietically expressed homeobox. (270 aa)    
Predicted Functional Partners:
CDKAL1
CDK5 regulatory subunit associated protein 1 like 1.
      
 0.835
SLC30A8
Solute carrier family 30 member 8.
      
 0.803
OTX2
Orthodenticle homeobox 2.
   
  
 0.796
FOXA2
Forkhead box A2.
   
 
 0.786
ZNF366
Zinc finger protein 366.
   
 
 0.781
GLIS1
GLIS family zinc finger 1.
    
 
 0.753
GATA6
Transcription factor GATA-6.
   
 
 0.737
EIF4E
Uncharacterized protein.
    
 
 0.720
TCF7L2
Transcription factor 7 like 2.
      
 0.706
POU5F1
POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency; Belongs to the POU transcription factor family. Class-5 subfamily.
   
  
 0.682
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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