Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
E2F2E2F transcription factor 2. (437 aa)    
Predicted Functional Partners:
RB1
Retinoblastoma-associated protein.
   
 0.998
TFDP2
Uncharacterized protein.
   
 0.991
E2F1
E2F transcription factor 1.
  
0.985
RBL2
RB transcriptional corepressor like 2.
   
 0.984
TFDP1
Transcription factor.
   
 0.977
CCNA2
Cyclin-A2; Belongs to the cyclin family.
   
 0.976
RBL1
RB transcriptional corepressor like 1.
   
 0.974
CCNA1
Cyclin-A1 isoform a; Belongs to the cyclin family.
   
 0.972
E2F3
E2F transcription factor 3.
  
 
0.939
ENSMMUP00000061681
Transcription factor.
   
 0.858
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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