Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADRA2BAdrenoceptor alpha 2B. (445 aa)    
Predicted Functional Partners:
ADRA2C
Adrenoceptor alpha 2C.
  
  
0.935
ADRA2A
Adrenoceptor alpha 2A.
  
  
0.934
GNA12
G protein subunit alpha 12.
   
  0.923
GNA13
G protein subunit alpha 13.
    
  0.919
GNA11
Guanine nucleotide-binding protein subunit alpha-11.
    
 0.915
GNAQ
Guanine nucleotide-binding protein G(Q) subunit alpha.
    
 0.915
GNG7
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.899
GNG4
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
    
 0.895
GNB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3.
    
 0.884
GNB5
G protein subunit beta 5.
   
  0.840
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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