Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PIGOPhosphatidylinositol glycan anchor biosynthesis class O. (1104 aa)    
Predicted Functional Partners:
PIGF
Phosphatidylinositol glycan anchor biosynthesis class F.
    
 0.994
PIGZ
Mannosyltransferase.
     
 0.986
PIGB
Mannosyltransferase.
   
 
 0.983
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
   
0.961
DPM1
Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
   
 
 0.815
PIGA
PIGA domain-containing protein.
      
 0.775
ALX3
ALX homeobox 3.
      
 0.764
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
    
 
 0.715
SEMA6B
Semaphorin 6B; Belongs to the semaphorin family.
     
 0.703
NCKAP1
Nck-associated protein 1 isoform 2.
     
 0.690
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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