Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM92BFamily with sequence similarity 92 member B. (302 aa)    
Predicted Functional Partners:
CTRB2
Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family.
      
 0.898
DSTYK
Dual serine/threonine and tyrosine protein kinase; Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase- independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.
   
 
 0.781
SPINK14
Serine peptidase inhibitor, Kazal type 14 (putative).
      
 0.768
SPINK6
Serine peptidase inhibitor, Kazal type 6.
      
 0.768
RHOH
Rho-related GTP-binding protein RhoH.
    
 0.744
SIX6
SIX homeobox 6.
      
 0.668
KLF5
Uncharacterized protein.
   
 0.647
PSTPIP1
Proline-serine-threonine phosphatase interacting protein 1.
   
  
 0.644
TXNDC12-2
Thioredoxin domain-containing protein.
   
 0.596
DYDC2
DPY30 domain containing 2.
   
 0.580
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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