Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBR1T-box brain transcription factor 1. (682 aa)    
Predicted Functional Partners:
PAX6
Uncharacterized protein.
   
 0.918
SATB2
DNA-binding protein SATB.
   
 
 0.915
CUX1
Homeobox protein cut-like.
    
 
 0.914
FOXG1
Forkhead box G1.
   
 
 0.905
EMX1
Homeobox protein EMX1.
    
 0.892
FEZF2
FEZ family zinc finger 2.
   
 
 0.874
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
    
 
 0.816
GFAP
Glial fibrillary acidic protein; Belongs to the intermediate filament family.
   
  
 0.811
FOXP2
Forkhead box protein P2; Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels (By similarity).
    
 
 0.808
DLX2
Distal-less homeobox 2.
   
 
 0.808
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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