Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CDKN2DCyclin-dependent kinase 4 inhibitor D. (166 aa)    
Predicted Functional Partners:
CDK6
Cyclin dependent kinase 6; Belongs to the protein kinase superfamily.
    
 0.996
CDK4
Cyclin-dependent kinase 4; Belongs to the protein kinase superfamily.
    
 0.995
CCND3
Cyclin D3; Belongs to the cyclin family.
   
 0.958
CCND1
Uncharacterized protein; Belongs to the cyclin family.
    
 0.951
CDKN1B
Cyclin-dependent kinase inhibitor 1B.
   
 0.705
CDK3
Cyclin dependent kinase 3; Belongs to the protein kinase superfamily.
    
 0.667
CDK1
Cyclin dependent kinase 1; Belongs to the protein kinase superfamily.
    
 0.624
CDKN1A
Cyclin-dependent kinase inhibitor 1.
    
 0.615
CDKN1C
Cyclin dependent kinase inhibitor 1C.
    
 0.590
RASIP1
Ras interacting protein 1.
   
 0.569
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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