Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SHPRHE3 ubiquitin-protein ligase SHPRH isoform a. (1683 aa)    
Predicted Functional Partners:
PCNA
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.946
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 0.934
ENSMMUP00000058534
UBIQUITIN_CONJUGAT_2 domain-containing protein.
    
 0.800
UBE2N
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.782
UBE2V2
Ubiquitin-conjugating enzyme E2 variant 2.
    
 0.765
RBBP7
RB binding protein 7, chromatin remodeling factor.
    
 0.757
ZNF609
C2H2-type domain-containing protein.
   
  
 0.731
PGM2
Phosphoglucomutase 2.
   
    0.710
USP28
Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family.
   
 0.689
FBXW7
F-box/WD repeat-containing protein 7 isoform 1.
   
 0.678
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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