Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FAR1Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols. (515 aa)    
Predicted Functional Partners:
GNPAT
Dihydroxyacetone phosphate acyltransferase.
 
    
 0.989
AGPS
Alkylglycerone-phosphate synthase; Catalyzes the exchange of an acyl for a long-chain alkyl group and the formation of the ether bond in the biosynthesis of ether phospholipids; Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
  
  
 0.922
FAR2
Fatty acyl-CoA reductase; Catalyzes the reduction of fatty acyl-CoA to fatty alcohols.
  
  
0.903
PEX7
Peroxisomal biogenesis factor 7.
      
 0.858
PEX5
Peroxisomal biogenesis factor 5.
      
 0.783
NUDCD1
NudC domain-containing protein 1 isoform 1.
    
   0.705
RALGAPB
Ral GTPase activating protein non-catalytic beta subunit.
   
  
 0.691
ACAA1
Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family.
   
  
 0.690
SYT8
Synaptotagmin 8.
      
 0.604
CGA
Glycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH, follitropin/follicle stimulating hormone/FSH and choriogonadotropin/CG. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways.
    
 
 0.593
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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