Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STING1Stimulator of interferon protein. (379 aa)    
Predicted Functional Partners:
TBK1
Serine/threonine-protein kinase TBK1.
   
 0.999
MAVS
Mitochondrial antiviral-signaling protein isoform 1.
    
 0.996
IKBKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon isoform 1.
   
 0.993
MNDA
Gamma-interferon-inducible protein 16 isoform 2.
   
 0.988
IRF3
Interferon regulatory factor 3.
    
 0.984
DDX41
DEAD-box helicase 41.
    
 0.978
TRIM32
E3 ubiquitin-protein ligase TRIM32.
   
 0.977
CGAS
Cyclic GMP-AMP synthase.
    
 0.907
RNF5
E3 ubiquitin-protein ligase RNF5.
    
 
 0.859
TRAF3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 
 0.832
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.