Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ERG28Putative ergosterol biosynthetic protein 28. (140 aa)    
Predicted Functional Partners:
HSD17B7
Hydroxysteroid 17-beta dehydrogenase 7.
   
 
 0.945
LSS
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
    
 
 0.900
NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; Belongs to the 3-beta-HSD family.
   
 
 0.872
SC5D
Lathosterol oxidase; Belongs to the sterol desaturase family.
   
 
 0.847
SIGMAR1
Sigma non-opioid intracellular receptor 1 isoform 1.
   
 
 0.842
FDFT1
Uncharacterized protein.
   
 
 0.835
MARCHF6
Membrane associated ring-CH-type finger 6.
      
 0.823
DHCR7
7-dehydrocholesterol reductase.
   
 
 0.765
CH25H
Fatty acid hydroxylase domain-containing protein; Belongs to the sterol desaturase family.
   
 
 0.703
MSMO1
C-4 methylsterol oxidase isoform 1; Belongs to the sterol desaturase family.
   
 
 0.703
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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