Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FBXL22F-box and leucine rich repeat protein 22. (226 aa)    
Predicted Functional Partners:
FBXW10
WD_REPEATS_REGION domain-containing protein.
    
 0.823
FBXO48
F-box domain-containing protein.
      
 0.779
ECT2L
Epithelial cell transforming 2 like.
    
 
 0.768
SKP1-2
Uncharacterized protein; Belongs to the SKP1 family.
    
 0.751
FBXO25
F-box only protein 25 isoform 1.
     
 0.722
FBXL13
F-box and leucine rich repeat protein 13.
      
 0.706
FBXL15
F-box domain-containing protein.
      
 0.691
FBXL7
F-box/LRR-repeat protein 7.
      
 0.687
LRRC29
Leucine rich repeat containing 29.
      
 0.687
CUL1
Cullin 1; Belongs to the cullin family.
    
 0.666
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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