Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 1. (1221 aa)    
Predicted Functional Partners:
ARF6
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
    
 0.977
ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3.
  
 
 
0.971
SH3KBP1
SH3 domain containing kinase binding protein 1.
   
 
 0.916
ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2.
  
 
 
0.902
GRB2
Growth factor receptor-bound protein 2 isoform 1.
    
 
 0.837
PXN
Paxillin.
   
 
 0.811
CRK
CRK proto-oncogene, adaptor protein.
    
 
 0.806
ARF4
ADP-ribosylation factor 4; Belongs to the small GTPase superfamily. Arf family.
    
 0.793
CTTN
SH3 domain-containing protein.
   
 
 0.788
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
   
 
 0.782
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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