Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
SEMA6DSemaphorin-6D isoform 4; Belongs to the semaphorin family. (1086 aa)    
Predicted Functional Partners:
PLXNA1
Plexin A1.
    
0.729
PLXNA3
Plexin A3.
    
0.705
TMEM38B
Trimeric intracellular cation channel type B.
      
 0.671
NRP1
Neuropilin; Belongs to the neuropilin family.
    
 0.634
SLC25A21
Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.627
PLXNA2
Plexin A2.
    
0.616
SLIT1
Slit guidance ligand 1.
      
 0.616
PLXND1
Plexin D1.
    
 0.615
PLXNA4
Plexin A4.
    
0.611
PLXNC1
Sema domain-containing protein.
   
 0.607
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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