Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SP140SP140 nuclear body protein. (860 aa)    
Predicted Functional Partners:
SUGCT
Succinyl-CoA:glutarate-CoA transferase.
    
 
 0.759
FAM91A1
Family with sequence similarity 91 member A1.
      
 0.758
UBE2I
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.706
CBX5
Heterochromatin protein 1-like protein alpha.
    
 0.635
SUMO1
Small ubiquitin-related modifier.
    
 0.634
PCGF5
Polycomb group ring finger 5.
      
 0.631
ORMDL3
ORMDL sphingolipid biosynthesis regulator 3.
      
 0.624
COL24A1
Collagen type XXIV alpha 1 chain.
    
 0.569
ZNF804A
Zinc finger protein 804A.
     
 0.539
PTGER4
Prostaglandin E2 receptor EP4 subtype; Belongs to the G-protein coupled receptor 1 family.
     
 0.532
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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