Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (555 aa)    
Predicted Functional Partners:
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
   
 0.999
PIGT
Phosphatidylinositol glycan anchor biosynthesis class T.
   
 0.999
PIGU
Phosphatidylinositol glycan anchor biosynthesis class U.
   
 0.998
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
   
 0.997
PGAP1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi.
    
 0.928
PIGG
Phosphatidylinositol glycan anchor biosynthesis class G.
   
 0.926
PIGF
Phosphatidylinositol glycan anchor biosynthesis class F.
     
 0.919
PRSS50
Uncharacterized protein; Belongs to the peptidase S1 family.
    
   0.698
PIGV
GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis.
   
 
 0.547
CAPNS1
Uncharacterized protein.
     
  0.540
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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