Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LCTLactase. (1928 aa)    
Predicted Functional Partners:
GLB1
Beta-galactosidase.
  
 
 0.946
GALM
Aldose 1-epimerase; Converts alpha-aldose to the beta-anomer.
  
 
 0.915
LALBA
Lactose synthase B protein; Belongs to the glycosyl hydrolase 22 family.
   
 
 0.909
G6PC2
Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.
     
 0.908
G6PC3
Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.
     
 0.908
G6PC
Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.
     
 0.906
GLA
Alpha-galactosidase.
     
 0.905
HK1
Hexokinase 1.
   
 
 0.904
AKR1B1
Aldo_ket_red domain-containing protein.
   
 
 0.904
GCK
Phosphotransferase.
   
 
 0.904
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (16%) [HD]