STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TDRD7Tudor domain-containing protein 7. (1098 aa)    
Predicted Functional Partners:
PIWIL2
Piwi like-2 protein; Belongs to the argonaute family.
   
 0.829
TDRD9
Tudor domain containing 9.
   
 0.828
PIWIL3
Uncharacterized protein; Belongs to the argonaute family.
   
 0.734
CRYBB2
Uncharacterized protein; Belongs to the beta/gamma-crystallin family.
      
 0.699
LCTL
Lactase like; Belongs to the glycosyl hydrolase 1 family.
      
 0.684
PLD6
Phospholipase D family member 6.
   
  
 0.680
SPATA19
Spermatogenesis associated 19.
   
  
 0.655
TNP2
Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction.
   
  
 0.655
PIWIL4
Uncharacterized protein; Belongs to the argonaute family.
   
 0.653
CRYAA
Alpha-crystallin A chain; Contributes to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
    
 
 0.653
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.