Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGAP11ARho GTPase activating protein 11A. (1023 aa)    
Predicted Functional Partners:
KIF11
Kinesin-like protein KIF11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
   
  
 0.902
CENPF
Centromere protein F.
   
  
 0.900
ASPM
Abnormal spindle-like microcephaly-associated protein homolog; Probable role in mitotic spindle regulation and coordination of mitotic processes. May have a preferential role in regulating neurogenesis (By similarity).
   
 
 0.896
BUB1B
BUB1 mitotic checkpoint serine/threonine kinase B.
   
  
 0.891
NEK2
Serine/threonine-protein kinase Nek2 isoform 1.
   
  
 0.882
TTK
TTK protein kinase.
   
  
 0.882
DLGAP5
DLG associated protein 5.
   
  
 0.878
BUB1
BUB1 mitotic checkpoint serine/threonine kinase.
   
  
 0.875
TOP2A
DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks.
   
  
 0.874
CCNA2
Cyclin-A2; Belongs to the cyclin family.
   
  
 0.866
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: medium (70%) [HD]