Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ZNRF4Zinc and ring finger 4. (429 aa)    
Predicted Functional Partners:
RNF175
Ring finger protein 175.
      
 0.876
RNF186
Ring finger protein 186.
   
  
 0.876
RNF182
E3 ubiquitin-protein ligase RNF182.
      
 0.875
RNF183
Ring finger protein 183.
    
 
 0.848
CHMP3
E3 ubiquitin-protein ligase RNF103 isoform 1.
   
 
 0.673
CGRRF1
Cell growth regulator with RING finger domain protein 1.
    
 
 0.647
RNF223
Ring finger protein 223.
    
 
 0.641
RNFT2
Ring finger protein, transmembrane 2.
      
 0.640
AP3S1
Adaptor related protein complex 3 subunit sigma 1.
    
 
 0.635
RNFT1
Ring finger protein, transmembrane 1.
      
 0.602
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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