Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CRB1Crumbs cell polarity complex component 1. (1406 aa)    
Predicted Functional Partners:
CRB2
Crumbs cell polarity complex component 2.
   
 
0.919
MPP5
Membrane palmitoylated protein 5; Belongs to the MAGUK family.
    
 0.897
CRB3
Crumbs protein homolog 3 isoform b.
     
 0.692
PATJ
PATJ crumbs cell polarity complex component.
    
 0.635
EPB41L5
Erythrocyte membrane protein band 4.1 like 5.
    
 
 0.598
KCNT2
Potassium sodium-activated channel subfamily T member 2.
      
 0.569
LLGL2
LLGL scribble cell polarity complex component 2.
    
 
 0.532
DCHS1
Dachsous cadherin-related 1.
    
 0.531
DCHS2
Dachsous cadherin-related 2.
    
 0.531
COG6
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
    
 
 0.516
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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