Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CANXCalnexin. (592 aa)    
Predicted Functional Partners:
CALR
Calreticulin.
   
0.981
PDIA3
Protein disulfide-isomerase.
   
 0.979
HSPA5
78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.
   
 0.971
LOC114672113
Protein disulfide-isomerase A3.
   
 0.969
SSR1
Uncharacterized protein.
   
 
 0.944
HSP90B1
Endoplasmin.
   
 
 0.943
ENSMMUP00000043660
Uncharacterized protein.
   
 
 0.924
PRKCSH
Protein kinase C substrate 80K-H.
   
 0.918
VCP
Uncharacterized protein; Belongs to the AAA ATPase family.
   
 
 0.911
EDEM1
alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family.
   
 
 0.908
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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