LTC4S protein (Macaca mulatta) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

LTC4S

Leukotriene C4 synthase. (150 aa)

Predicted Functional Partners:

LTA4H

0.969

ALOX5

0.937

GGT5

0.921

LOC700936

0.914

GGT1

0.914

MGST1

0.834

PTGES

0.675

CYSLTR1

0.667

HSD17B13

0.650

CYSLTR2

0.650

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALOX5	LTA4H	ENSMMUP00000048345	ENSMMUP00000050474	Arachidonate 5-lipoxygenase.	Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.	0.962
ALOX5	LTC4S	ENSMMUP00000048345	ENSMMUP00000016249	Arachidonate 5-lipoxygenase.	Leukotriene C4 synthase.	0.937
CYSLTR1	CYSLTR2	ENSMMUP00000017587	ENSMMUP00000066951	Cysteinyl leukotriene receptor 1.	Cysteinyl leukotriene receptor 2.	0.971
CYSLTR1	LTC4S	ENSMMUP00000017587	ENSMMUP00000016249	Cysteinyl leukotriene receptor 1.	Leukotriene C4 synthase.	0.667
CYSLTR2	CYSLTR1	ENSMMUP00000066951	ENSMMUP00000017587	Cysteinyl leukotriene receptor 2.	Cysteinyl leukotriene receptor 1.	0.971
CYSLTR2	LTC4S	ENSMMUP00000066951	ENSMMUP00000016249	Cysteinyl leukotriene receptor 2.	Leukotriene C4 synthase.	0.650
GGT1	GGT5	ENSMMUP00000065187	ENSMMUP00000069000	Uncharacterized protein.	Gamma-glutamyltransferase 5.	0.975
GGT1	LOC700936	ENSMMUP00000065187	ENSMMUP00000061317	Uncharacterized protein.	Uncharacterized protein.	0.900
GGT1	LTC4S	ENSMMUP00000065187	ENSMMUP00000016249	Uncharacterized protein.	Leukotriene C4 synthase.	0.914
GGT1	MGST1	ENSMMUP00000065187	ENSMMUP00000061026	Uncharacterized protein.	Uncharacterized protein.	0.701
GGT5	GGT1	ENSMMUP00000069000	ENSMMUP00000065187	Gamma-glutamyltransferase 5.	Uncharacterized protein.	0.975
GGT5	LOC700936	ENSMMUP00000069000	ENSMMUP00000061317	Gamma-glutamyltransferase 5.	Uncharacterized protein.	0.972
GGT5	LTC4S	ENSMMUP00000069000	ENSMMUP00000016249	Gamma-glutamyltransferase 5.	Leukotriene C4 synthase.	0.921
GGT5	MGST1	ENSMMUP00000069000	ENSMMUP00000061026	Gamma-glutamyltransferase 5.	Uncharacterized protein.	0.698
HSD17B13	LTC4S	ENSMMUP00000054645	ENSMMUP00000016249	17-beta-hydroxysteroid dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Leukotriene C4 synthase.	0.650
LOC700936	GGT1	ENSMMUP00000061317	ENSMMUP00000065187	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC700936	GGT5	ENSMMUP00000061317	ENSMMUP00000069000	Uncharacterized protein.	Gamma-glutamyltransferase 5.	0.972
LOC700936	LTC4S	ENSMMUP00000061317	ENSMMUP00000016249	Uncharacterized protein.	Leukotriene C4 synthase.	0.914
LOC700936	MGST1	ENSMMUP00000061317	ENSMMUP00000061026	Uncharacterized protein.	Uncharacterized protein.	0.698
LTA4H	ALOX5	ENSMMUP00000050474	ENSMMUP00000048345	Leukotriene A(4) hydrolase; Belongs to the peptidase M1 family.	Arachidonate 5-lipoxygenase.	0.962