Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FAM181AFamily with sequence similarity 181 member A. (354 aa)    
Predicted Functional Partners:
LRRC43
Leucine rich repeat containing 43.
      
 0.534
TTC7B
Tetratricopeptide repeat domain 7B.
      
 0.524
PRIMA1
Proline rich membrane anchor 1.
      
 0.519
IQCK
Uncharacterized protein.
      
 0.513
CFAP47
Calponin-homology (CH) domain-containing protein.
      
 0.499
TEX43
Uncharacterized protein.
      
 0.498
TEAD3
Transcriptional enhancer factor TEF-5; Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
    
 
 0.488
TEAD1
TEA domain transcription factor 1.
    
 
 0.488
TEAD2
TEA domain transcription factor 2.
    
 
 0.488
SIPA1L1
Signal-induced proliferation-associated 1-like protein 1.
      
 0.476
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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