Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
DDX58Putative ATP-dependent RNA helicase DDX58. (925 aa)    
Predicted Functional Partners:
MAVS
Mitochondrial antiviral-signaling protein isoform 1.
    
 0.999
ISG15
Ubiquitin-like protein ISG15.
   
 0.999
DHX58
DExH-box helicase 58.
   
0.992
RNF125
E3 ubiquitin-protein ligase RNF125.
    
 0.988
OASL
2'-5'-oligoadenylate synthetase like.
   
 0.988
EIF2AK2
Eukaryotic translation initiation factor 2 alpha kinase 2.
   
 0.968
RNF135
Ring finger protein 135.
   
 0.963
RSAD2
Radical S-adenosyl methionine domain-containing protein 2.
   
  
 0.953
STAT1
Signal transducer and activator of transcription.
   
 0.953
CYLD
CYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family.
    
 0.951
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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