Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
REC8REC8 meiotic recombination protein. (565 aa)    
Predicted Functional Partners:
SMC1A
Structural maintenance of chromosomes protein.
   
 0.990
ESPL1
Extra spindle pole bodies like 1, separase.
   
 0.990
SMC3
Structural maintenance of chromosomes protein.
   
 0.988
RAD21L1
RAD21 cohesin complex component like 1.
    
0.984
RAD21
Double-strand-break repair protein rad21 homolog.
    
0.980
STAG3
SCD domain-containing protein.
   
 0.974
SMC1B
Structural maintenance of chromosomes protein.
   
 0.974
STAG2
Cohesin subunit SA-2 isoform a.
   
 0.943
PPP2CB
Serine/threonine-protein phosphatase.
   
 0.942
PPP2R1A
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform.
     
 0.940
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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