Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHA8Uncharacterized protein. (519 aa)    
Predicted Functional Partners:
ARF1
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
   
 0.875
NARF
Nuclear prelamin A recognition factor; Belongs to the NARF family.
      
 0.810
CASC4
Cancer susceptibility 4.
      
 0.770
MATN3
Matrilin 3.
      
 0.682
MNAT1
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
      
 0.659
TMTC4
Transmembrane O-mannosyltransferase targeting cadherins 4.
      
 0.624
TRIP4
Thyroid hormone receptor interactor 4.
      
 0.618
PLEKHA3
Pleckstrin homology domain-containing family A member 3.
    
  0.616
ENSMMUP00000053024
ARL17 domain-containing protein.
   
 0.616
ENSMMUP00000066507
Uncharacterized protein.
   
 0.616
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
Server load: low (22%) [HD]