Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
TBX20T-box transcription factor TBX20. (447 aa)    
Predicted Functional Partners:
NKX2-5
NK2 homeobox 5.
   
 0.951
GATA4
GATA binding protein 4.
   
 0.939
SLC25A21
Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family.
    
   0.902
PHF13
PHD domain-containing protein.
    
   0.902
ISL1
ISL LIM homeobox 1.
   
 0.859
GATA5
GATA binding protein 5.
   
 0.832
MEF2C
Myocyte-specific enhancer factor 2C isoform 1.
    
 0.800
TLE1
TLE family member 1, transcriptional corepressor.
    
 
 0.799
LOC706619
Uncharacterized protein.
    
 
 0.795
HAND2
BHLH domain-containing protein.
   
 
 0.779
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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