Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FCHSD1FCH and double SH3 domains 1. (688 aa)    
Predicted Functional Partners:
ITSN2
Intersectin 2.
   
 0.690
WASL
Neural Wiskott-Aldrich syndrome protein.
   
 0.618
WAS
WASP actin nucleation promoting factor.
   
 0.618
FNBP4
Formin binding protein 4.
    
 
 0.609
ITSN1
Intersectin 1.
   
 0.600
SNX18
Sorting nexin 18.
    
 
 0.552
SNX33
Sorting nexin.
    
 
 0.552
MAGI1
Membrane associated guanylate kinase, WW and PDZ domain containing 1.
    
 
 0.547
FNBP1
Formin binding protein 1.
      
 0.542
ARHGEF37
Rho guanine nucleotide exchange factor 37.
    
 
 0.539
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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