Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ME1Malic enzyme. (572 aa)    
Predicted Functional Partners:
PC
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.982
FH
Fumarate hydratase, mitochondrial.
  
 
 0.979
LDHC
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.966
LOC710798
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.964
PDHA1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.963
MDH1
Malate dehydrogenase.
  
 0.963
MDH2
Malate dehydrogenase.
  
 0.962
PKLR
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.962
PDHB
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 
 0.954
LDHAL6A
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.953
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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