Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
GAB4GRB2 associated binding protein family member 4. (992 aa)    
Predicted Functional Partners:
LRRC74B
Uncharacterized protein.
      
 0.905
CCT8L2
Chaperonin containing TCP1 subunit 8 like 2.
      
 0.899
GRB2
Growth factor receptor-bound protein 2 isoform 1.
    
 0.863
PTPN11
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
     
 0.697
PTPN6
Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.
     
 0.549
LZTR1
Leucine-zipper-like transcriptional regulator 1.
      
 0.527
SHC1
SHC-transforming protein 1 isoform 3.
     
 0.524
GRAP
Uncharacterized protein.
    
 0.518
GRAP2
GRB2 related adaptor protein 2.
    
 0.518
CRKL
Apoptosis inducing factor mitochondria associated 3.
      
 0.486
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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