Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ITGA2BIntegrin subunit alpha 2b; Belongs to the integrin alpha chain family. (1090 aa)    
Predicted Functional Partners:
ITGB3
Integrin beta; Belongs to the integrin beta chain family.
   
 0.999
VWF
Uncharacterized protein.
   
 0.991
TLN1
Talin 1.
   
 0.982
VTN
Uncharacterized protein.
   
 0.972
FN1
Fibronectin isoform 1 preproprotein.
    
 0.972
THBS1
Thrombospondin 1.
   
 0.966
TLN2
Talin 2.
   
 0.957
PTK2
Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.
    
 0.957
ITGB1
Integrin beta; Belongs to the integrin beta chain family.
   
 0.955
SRC
Tyrosine-protein kinase.
   
 0.950
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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