Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PDZRN3PDZ domain containing ring finger 3. (1066 aa)    
Predicted Functional Partners:
IGSF3
Immunoglobulin superfamily member 3.
    
 
 0.722
MTX2
Metaxin-2.
      
 0.662
CEP170B
Centrosomal protein 170B.
    
 
 0.649
MIB2
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.647
ZNF595
Zinc finger protein 595.
   
 0.628
ZNF473
Uncharacterized protein.
    
 0.625
ATXN7L3
Ataxin-7-like protein 3; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and EN [...]
    
 
 0.616
CASKIN1
CASK interacting protein 1.
    
 0.612
OR5L1
G_PROTEIN_RECEP_F1_2 domain-containing protein.
    
 0.610
NIPA2
Non-imprinted in Prader-Willi/Angelman syndrome region protein 2.
      
 0.581
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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