| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AFMID | APCS | ENSMMUP00000047726 | ENSMMUP00000008795 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Pentaxin. | 0.445 |
| AFMID | FMO5 | ENSMMUP00000047726 | ENSMMUP00000039222 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Dimethylaniline monooxygenase [N-oxide-forming]. | 0.692 |
| AFMID | NAXD | ENSMMUP00000047726 | ENSMMUP00000016632 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | 0.680 |
| AFMID | PHLDB1 | ENSMMUP00000047726 | ENSMMUP00000044230 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Pleckstrin homology like domain family B member 1. | 0.504 |
| APCS | AFMID | ENSMMUP00000008795 | ENSMMUP00000047726 | Pentaxin. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 0.445 |
| APCS | FMO5 | ENSMMUP00000008795 | ENSMMUP00000039222 | Pentaxin. | Dimethylaniline monooxygenase [N-oxide-forming]. | 0.460 |
| APCS | NAXD | ENSMMUP00000008795 | ENSMMUP00000016632 | Pentaxin. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | 0.551 |
| APCS | PHLDB1 | ENSMMUP00000008795 | ENSMMUP00000044230 | Pentaxin. | Pleckstrin homology like domain family B member 1. | 0.471 |
| EDC3 | GART | ENSMMUP00000072782 | ENSMMUP00000054383 | Enhancer of mRNA-decapping protein 3. | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | 0.568 |
| EDC3 | NAXD | ENSMMUP00000072782 | ENSMMUP00000016632 | Enhancer of mRNA-decapping protein 3. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | 0.739 |
| EDC3 | YJEFN3 | ENSMMUP00000072782 | ENSMMUP00000014899 | Enhancer of mRNA-decapping protein 3. | YjeF N-terminal domain containing 3. | 0.529 |
| FMO5 | AFMID | ENSMMUP00000039222 | ENSMMUP00000047726 | Dimethylaniline monooxygenase [N-oxide-forming]. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 0.692 |
| FMO5 | APCS | ENSMMUP00000039222 | ENSMMUP00000008795 | Dimethylaniline monooxygenase [N-oxide-forming]. | Pentaxin. | 0.460 |
| FMO5 | NAXD | ENSMMUP00000039222 | ENSMMUP00000016632 | Dimethylaniline monooxygenase [N-oxide-forming]. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | 0.620 |
| FMO5 | OGDHL | ENSMMUP00000039222 | ENSMMUP00000000377 | Dimethylaniline monooxygenase [N-oxide-forming]. | Transket_pyr domain-containing protein. | 0.487 |
| FMO5 | PHLDB1 | ENSMMUP00000039222 | ENSMMUP00000044230 | Dimethylaniline monooxygenase [N-oxide-forming]. | Pleckstrin homology like domain family B member 1. | 0.510 |
| GART | EDC3 | ENSMMUP00000054383 | ENSMMUP00000072782 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | Enhancer of mRNA-decapping protein 3. | 0.568 |
| GART | NAXD | ENSMMUP00000054383 | ENSMMUP00000016632 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | ATP-dependent (S)-NAD(P)H-hydrate dehydratase; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrD/CARKD family. | 0.597 |
| GART | NAXE | ENSMMUP00000054383 | ENSMMUP00000042613 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | NAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. | 0.568 |
| GART | YJEFN3 | ENSMMUP00000054383 | ENSMMUP00000014899 | Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family. | YjeF N-terminal domain containing 3. | 0.568 |
