MBD4 protein (Macaca mulatta) - STRING interaction network

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MBD4

Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein. (572 aa)

Predicted Functional Partners:

TDG

0.813

DEK

0.751

SMUG1

0.725

ENSMMUP00000070845

0.651

DNMT1

0.644

MLH1

0.634

MBD3

0.600

DNMT3A

0.596

MBD6

0.595

KCNK4

0.585

Your Current Organism:

Macaca mulatta

NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DEK	MBD4	ENSMMUP00000057509	ENSMMUP00000016705	Protein DEK isoform 1.	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	0.751
DEK	TDG	ENSMMUP00000057509	ENSMMUP00000028034	Protein DEK isoform 1.	Thymine DNA glycosylase.	0.607
DNMT1	DNMT3A	ENSMMUP00000019170	ENSMMUP00000025595	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.994
DNMT1	MBD3	ENSMMUP00000019170	ENSMMUP00000047540	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Methyl-CpG-binding domain protein 3.	0.433
DNMT1	MBD4	ENSMMUP00000019170	ENSMMUP00000016705	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	0.644
DNMT1	TDG	ENSMMUP00000019170	ENSMMUP00000028034	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Thymine DNA glycosylase.	0.709
DNMT3A	DNMT1	ENSMMUP00000025595	ENSMMUP00000019170	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.994
DNMT3A	MBD4	ENSMMUP00000025595	ENSMMUP00000016705	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	0.596
DNMT3A	TDG	ENSMMUP00000025595	ENSMMUP00000028034	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Thymine DNA glycosylase.	0.546
ENSMMUP00000070845	MBD4	ENSMMUP00000070845	ENSMMUP00000016705	Uncharacterized protein.	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	0.651
ENSMMUP00000070845	TDG	ENSMMUP00000070845	ENSMMUP00000028034	Uncharacterized protein.	Thymine DNA glycosylase.	0.513
KCNK4	MBD4	ENSMMUP00000037444	ENSMMUP00000016705	Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	0.585
MBD3	DNMT1	ENSMMUP00000047540	ENSMMUP00000019170	Methyl-CpG-binding domain protein 3.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.433
MBD3	MBD4	ENSMMUP00000047540	ENSMMUP00000016705	Methyl-CpG-binding domain protein 3.	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	0.600
MBD3	MBD6	ENSMMUP00000047540	ENSMMUP00000014795	Methyl-CpG-binding domain protein 3.	Methyl-CpG-binding domain protein 6.	0.691
MBD4	DEK	ENSMMUP00000016705	ENSMMUP00000057509	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	Protein DEK isoform 1.	0.751
MBD4	DNMT1	ENSMMUP00000016705	ENSMMUP00000019170	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.644
MBD4	DNMT3A	ENSMMUP00000016705	ENSMMUP00000025595	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	DNA methyltransferase 3 alpha; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.596
MBD4	ENSMMUP00000070845	ENSMMUP00000016705	ENSMMUP00000070845	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	Uncharacterized protein.	0.651
MBD4	KCNK4	ENSMMUP00000016705	ENSMMUP00000037444	Methyl-CpG-binding domain protein 4; Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.	Potassium two pore domain channel subfamily K member 4; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.	0.585

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