Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LRRC8DLeucine-rich repeat-containing protein 8D. (858 aa)    
Predicted Functional Partners:
LRRC8A
Leucine-rich repeat-containing protein 8A.
   
  0.961
LRRC8B
Leucine-rich repeat-containing protein 8B.
    
  0.877
LRRIQ4
Leucine rich repeats and IQ motif containing 4.
  
 
0.596
LRRC8C
Leucine-rich repeat-containing protein 8C.
   
  0.522
LRRC8E
Leucine rich repeat containing 8 VRAC subunit E.
   
  0.522
TTYH2
Protein tweety homolog; Probable chloride channel; Belongs to the tweety family.
      
 0.485
KERA
Keratocan.
  
     0.476
AQP4
Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 0.468
LRRC32
Leucine rich repeat containing 32.
  
     0.464
GRM5
Metabotropic glutamate receptor 5 isoform a.
    
 
 0.448
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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