Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
F6TB05_MACMUUncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)    
Predicted Functional Partners:
ECI2
Enoyl-CoA delta isomerase 2.
  
 0.893
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 0.893
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
  
 0.853
HADH
Hydroxyacyl-CoA dehydrogenase.
  
 0.805
HSDL2
Hydroxysteroid dehydrogenase-like protein 2 isoform 1.
  
 0.790
CRYL1
Crystallin lambda 1.
  
 0.734
EHHADH
Enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.708
IDH2
Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 0.684
ECI1
Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.665
OXCT1
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.660
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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