STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)    
Predicted Functional Partners:
PTGES
Prostaglandin E synthase.
     
 0.952
PTGES2
Prostaglandin E synthase 2; Belongs to the GST superfamily.
     
 0.944
ALOX15
Arachidonate 15-lipoxygenase.
   
 
 0.944
PTGIS
Prostacyclin synthase; Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2); Belongs to the cytochrome P450 family.
   
 0.943
HPGDS
Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily.
     
 0.942
PTGES3
CS domain-containing protein.
     
 0.939
PTGS2
Prostaglandin-endoperoxide synthase 2.
  
0.931
ALOX12B
Arachidonate 12-lipoxygenase, 12R type.
   
 
 0.925
CYP2J2
Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family.
   
 
 0.923
PTGDS
Prostaglandin-H2 D-isomerase; Belongs to the calycin superfamily. Lipocalin family.
     
 0.918
Your Current Organism:
Macaca mulatta
NCBI taxonomy Id: 9544
Other names: M. mulatta, Rhesus monkey, rhesus macaque, rhesus macaques, rhesus monkeys
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.