| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARSA | GALC | ENSMMUP00000070783 | ENSMMUP00000051400 | Arylsulfatase A. | Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon; Belongs to the glycosyl hydrolase 59 family. | 0.977 |
| ARSA | GBA | ENSMMUP00000070783 | ENSMMUP00000068053 | Arylsulfatase A. | Glucosylceramidase. | 0.421 |
| ARSA | GLA | ENSMMUP00000070783 | ENSMMUP00000048316 | Arylsulfatase A. | Alpha-galactosidase. | 0.953 |
| ARSA | GM2A | ENSMMUP00000070783 | ENSMMUP00000030116 | Arylsulfatase A. | GM2 ganglioside activator. | 0.608 |
| ARSA | PSAP | ENSMMUP00000070783 | ENSMMUP00000017026 | Arylsulfatase A. | Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. | 0.828 |
| ARSA | PSAPL1 | ENSMMUP00000070783 | ENSMMUP00000066107 | Arylsulfatase A. | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. | 0.711 |
| GALC | ARSA | ENSMMUP00000051400 | ENSMMUP00000070783 | Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon; Belongs to the glycosyl hydrolase 59 family. | Arylsulfatase A. | 0.977 |
| GALC | GBA | ENSMMUP00000051400 | ENSMMUP00000068053 | Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon; Belongs to the glycosyl hydrolase 59 family. | Glucosylceramidase. | 0.959 |
| GALC | GLA | ENSMMUP00000051400 | ENSMMUP00000048316 | Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon; Belongs to the glycosyl hydrolase 59 family. | Alpha-galactosidase. | 0.950 |
| GALC | GM2A | ENSMMUP00000051400 | ENSMMUP00000030116 | Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon; Belongs to the glycosyl hydrolase 59 family. | GM2 ganglioside activator. | 0.409 |
| GALC | PSAP | ENSMMUP00000051400 | ENSMMUP00000017026 | Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon; Belongs to the glycosyl hydrolase 59 family. | Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. | 0.762 |
| GALC | PSAPL1 | ENSMMUP00000051400 | ENSMMUP00000066107 | Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon; Belongs to the glycosyl hydrolase 59 family. | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. | 0.714 |
| GBA | ARSA | ENSMMUP00000068053 | ENSMMUP00000070783 | Glucosylceramidase. | Arylsulfatase A. | 0.421 |
| GBA | GALC | ENSMMUP00000068053 | ENSMMUP00000051400 | Glucosylceramidase. | Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon; Belongs to the glycosyl hydrolase 59 family. | 0.959 |
| GBA | GLA | ENSMMUP00000068053 | ENSMMUP00000048316 | Glucosylceramidase. | Alpha-galactosidase. | 0.533 |
| GBA | PSAP | ENSMMUP00000068053 | ENSMMUP00000017026 | Glucosylceramidase. | Prosaposin; Prosaposin: Behaves as a myelinotrophic and neurotrophic factor, these effects are mediated by its G-protein-coupled receptors, GPR37 and GPR37L1, undergoing ligand-mediated internalization followed by ERK phosphorylation signaling. | 0.865 |
| GBA | PSAPL1 | ENSMMUP00000068053 | ENSMMUP00000066107 | Glucosylceramidase. | Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids. | 0.865 |
| GLA | ARSA | ENSMMUP00000048316 | ENSMMUP00000070783 | Alpha-galactosidase. | Arylsulfatase A. | 0.953 |
| GLA | GALC | ENSMMUP00000048316 | ENSMMUP00000051400 | Alpha-galactosidase. | Galactocerebrosidase; Hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Enzyme with very low activity responsible for the lysosomal catabolism of galactosylceramide, a major lipid in myelin, kidney and epithelial cells of small intestine and colon; Belongs to the glycosyl hydrolase 59 family. | 0.950 |
| GLA | GBA | ENSMMUP00000048316 | ENSMMUP00000068053 | Alpha-galactosidase. | Glucosylceramidase. | 0.533 |